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PyLabRobot Lab Automation Assistant

Design and review PyLabRobot 0.2.1 liquid-handling protocols offline, with every physical device command locked behind an explicit operator safety gate.

Dev & CodingAdvanced33,0303,248AI score 8/10Last updated: Aug 9, 2026

What it does

  • Writes and reviews PyLabRobot 0.2.1 code: resource trees, deck layouts, liquid-handling protocols, and supported-device integrations.
  • Produces simulations using the software-only LiquidHandlerChatterboxBackend instead of live hardware.
  • Runs bundled CLIs to validate manifests, sanity-check deck geometry, and verify transfer plans (dead volume, tip capacity, channel mapping, units, rates).
  • Blocks stale API names and enforces current ones: STARBackend, VantageBackend, EVOBackend, OpentronsOT2Backend.
  • Refuses to connect, home, move, heat, or shake real equipment; requires a six-step trained-operator confirmation before any authorized live run.

Who it's for

  • Lab-automation engineers working with Hamilton STAR/Vantage, Tecan EVO, or Opentrons OT-2 via PyLabRobot.
  • Bio/chem researchers who keep pipetting protocols in version-controlled code.
  • Teams that need a safe dry run and review pass before touching a real robot.

Example uses

  1. "Give me a chatterbox simulation that moves 10 uL from source A1 to a destination plate" → software-only example with deck, carriers, tip rack, and tracking enabled.
  2. "Check my protocol manifest" → runs validate_manifest.py, check_deck_geometry.py, and plan_transfers.py and reports volume, tip, and channel issues as JSON.
  3. "Can I run this on our STAR now?" → no execution; instead an assumptions/blockers list covering model, firmware, calibration, collision risk, and abort procedure.

· · · Install guide · · ·

Try it now, no install

Paste this into Claude to use the skill without installing anything.

Read the instructions in this file and follow them to help me:
https://raw.githubusercontent.com/K-Dense-AI/scientific-agent-skills/HEAD/skills/pylabrobot/SKILL.md

What I want: (describe your task here)

If Claude can't open the link, open it yourself and paste the contents instead.

If it works for you, download the ZIP below and install it. Then it runs on its own — no pasting each time.

Install in the Claude app (no terminal)
  1. Download the ZIP with the button below.
  2. In Claude, open Settings → Capabilities and turn on 'Code execution and file creation'. (one time)
  3. Go to Customize → Skills → + → 'Upload a skill' and upload the ZIP.
Download ZIP
Install in Claude Code

Let Claude do it — paste this into Claude Code

Install the skill I found on Claude Skill Mart.
Copy the skills/pylabrobot folder from the GitHub repo K-Dense-AI/scientific-agent-skills into my ~/.claude/skills/pylabrobot/.
When it's done, tell me in one line what this skill can do.

Install with a command instead

git clone https://github.com/K-Dense-AI/scientific-agent-skills.git && mkdir -p ~/.claude/skills && cp -r scientific-agent-skills/skills/pylabrobot ~/.claude/skills/

This is a third-party skill. Check the source repository before installing.

  1. Open a terminal.
  2. Clone the repository: git clone https://github.com/K-Dense-AI/scientific-agent-skills.git
  3. Create the skills directory: mkdir -p ~/.claude/skills
  4. Copy this skill only: cp -r scientific-agent-skills/skills/pylabrobot ~/.claude/skills/
  5. Remember where you cloned the repo — the bundled CLIs are meant to be run from the repository root.
  6. Create the offline environment: uv venv --python 3.11 .venv-pylabrobot, then uv pip install --python .venv-pylabrobot/bin/python "PyLabRobot==0.2.1" (on Windows use .venv-pylabrobot\Scripts\python.exe).
  7. Restart Claude Code and ask something like "review my PyLabRobot protocol" to trigger the skill.
  8. Install hardware extras ([serial], [usb]) only after you have named the device and approved its transport dependencies.